Weight loss is increased with a self-directed behavioral lifestyle intervention

WEDNESDAY, Dec. 14, 2022 (HealthDay News) — A remotely delivered self-directed behavioral lifestyle intervention results in greater weight loss for adults with obesity than usual care at 12 months, but the difference is not it’s clinically important, according to a study published in the Dec. 13 issue of the Journal of the American Medical Association.

Katherine D. Hoerster, Ph.D., MPH, of the VA Puget Sound Healthcare System in Seattle, and colleagues randomly assigned 511 adults with a body mass index of 30 or more and less than 45 to an intervention or control remotely administered behavioral lifestyle group (254 and 257, respectively). The intervention group received self-directed training videos, brochures, and messages based on the Diabetes Prevention Program through an online platform or by mail for 12 months; both groups also received usual care.

The investigators found that the unadjusted mean weight at 12 months decreased from 102.7 to 99.8 kg in the intervention group and from 101.9 to 101.0 kg in the control group (adjusted mean difference between groups, −1.93, 97.5 percent confidence interval, −3.24 to −0.61, P = 0.001). Unadjusted mean 12-item Short Form Health Survey (SF-12) Physical Component Scores (PCS) decreased from 44.8 to 44.3 and from 44.5 to 43.2 at 12 months between intervention and control participants (adjusted mean difference between groups, 0.69; 97.5 percent confidence interval, −1.11 to 2.49; P = 0.39).

“The self-directed intervention in this study did not significantly improve SF-12 PCS scores compared with usual care,” the authors write. “This may be due to the modest effect of the intervention on weight.”

One author served as a paid scientific consultant for Health Mentor Inc.

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