Olfactory viral inflammation associated with accelerated onset of Alzheimer’s disease

Viruses can inflame and disrupt connections between the olfactory system, which governs the sense of smell, and the part of the brain associated with memory and learning, possibly accelerating the onset of Alzheimer’s disease, according to a new study from researchers of the University of Colorado Anschutz Medical Campus. The recommendationspublished Tuesday in the journal […]

SARS-CoV-2 hijacks cellular kinase CDK2 to promote viral RNA synthesis

CDKs support SARS-CoV-2 RdRp-mediated gene expression To identify cellular proteins that modulate the SARS-CoV-2 RNA synthesis, we first performed immunoprecipitation coupled with mass spectrometry (MS) to determine cellular proteins that associate with SARS-CoV-2 RdRp. Briefly, Flag-tagged nsp7, Flag-tagged nsp8, and Flag-tagged nsp12 plasmids were co-transfected into HEK293T cells, and the Flag-tagged proteins in cell lysates […]

UBC researchers identify a compound that shows early promise in stopping viral infections

Researchers at UBC’s Institute of Life Sciences have identified a compound that shows early promise in stopping infections from a range of coronaviruses, including all variants of SARS-CoV-2 and the common cold. The findings, published this week in Molecular Biomedicine, reveal a potential path toward antiviral treatments that could be used against many different pathogens. […]

10 of the most viral TikToks of 2022

As the year comes to a close, it’s time to review some of our favorite viral content from the past 12 months. From sweet little glimpses into the home lives of our favorite celebrities to major PSAs and daily doses of adorable content to DIY out-of-the-box inspo, it’s been a big year for TikTok. The […]

Why do viruses spread so easily in cold weather?

Previous studies by the current author have found that one component of the immune response against respiratory viruses involves the release of swarms of membrane-bound particles called extracellular vesicles (EVs) by cells lining the nasal cavity. EVs are membrane-bound particles that can carry a payload of DNA, RNA, and protein and are released by most […]